R&D Intern
Company: Legend Biotech
Location: Philadelphia
Posted on: March 5, 2026
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Job Description:
Legend Biotech is a global biotechnology company dedicated to
treating, and one day curing, life-threatening diseases.
Headquartered in Somerset, New Jersey, we are developing advanced
cell therapies across a diverse array of technology platforms,
including autologous and allogenic chimeric antigen receptor
T-cell, T-cell receptor (TCR-T), and natural killer (NK) cell-based
immunotherapy. From our three R&D sites around the world, we
apply these innovative technologies to pursue the discovery of
safe, efficacious and cutting-edge therapeutics for patients
worldwide. Legend Biotech entered into a global collaboration
agreement with Janssen, one of the pharmaceutical companies of
Johnson & Johnson, to jointly develop and commercialize
ciltacabtagene autolecuel (cilta-cel). Our strategic partnership is
designed to combine the strengths and expertise of both companies
to advance the promise of an immunotherapy in the treatment of
multiple myeloma. Legend Biotech is seeking a R&D Intern as
part of the Research & Early Development team based in
Philadelphia, PA . Role Overview The R&D Intern will support
research activities focused on cellular therapy and CAR-T
technology. This role involves analyzing cytotoxic potential of
CAR-T cells and other immune cells, performing cytokine analysis,
and correlating donor variability. The intern will also assist in
evaluating T cells generated with in-vivo CAR platforms and
contribute to data analysis and reporting. Key Responsibilities
Perform cytotoxicity assays and cytokine analysis using MSD assay.
Analyze CAR-T cells, macrophages, and other immune cells for
cytotoxic potential. Correlate cytotoxicity data across multiple
donors. Support in-vivo CAR platform evaluations. Analyze
experimental data and prepare reports for manager and team.
Maintain accurate laboratory records and follow SOPs. Requirements
College student (BS, MS, or PhD) in Life Science, Biomedical
Science, Biotechnology, Cell Science, Biology, Virology, Molecular
Biology, or STEM. Desired Academic Grade Level: Junior/Senior/
Graduate Student. Interest in cellular therapy and immunotherapy.
Knowledge of CAR-T, virus design, or immune cell assays preferred.
Ability to commit to lab bench work (70%) and desk work (30%).
Strong communication and organization skills. Skills You’ll Gain
Hands-on experience in CAR-T cell culture and transduction.
Exposure to in-vivo CAR platform development. Understanding of
immunotherapy approaches and assay techniques. Li-JR1 Li-Contract
Please note: These benefits are offered exclusively to permanent
full-time employees. Contractors are not eligible for benefits
through Legend Biotech. EEO Statement It is the policy of Legend
Biotech to provide equal employment opportunities without regard to
actual or perceived race, color, creed, religion, national origin,
ancestry, citizenship status, age, sex or gender (including
pregnancy, childbirth, related medical conditions and lactation),
gender identity or gender expression (including transgender
status), sexual orientation, marital status, military service and
veteran status, disability, genetic information, or any other
protected characteristic under applicable federal, state or local
laws or ordinances. Employment is at-will and may be terminated at
any time with or without cause or notice by the employee or the
company. For information related to our privacy policy, please
review: Legend Biotech Privacy Policy.
Keywords: Legend Biotech, Mount Vernon , R&D Intern, Science, Research & Development , Philadelphia, New York
